Article
The impact of FCN2 polymorphisms and haplotypes on the Ficolin-2 serum levels.
Scandinavian journal of immunology - 1 Apr 2007
Munthe-Fog L, Hummelshøj T, Hansen B E, Koch C, Madsen H O, Skjødt K, Garred P
Abstract excerpt
Ficolin-2 (L-ficolin), derived from the FCN2 gene, is an innate immunity pattern recognition molecule found in human serum in which inter-individual variation in serum appears to be under genetic control. To validate and extend this finding, we developed a sandwich ELISA for detection of human Ficolin-2 in serum samples and identified FCN2 genotypes with a Taq Man-based minor groove binder assay and by...
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