Article
Ficolin-2 levels and FCN2 haplotypes influence hepatitis B infection outcome in Vietnamese patients.
PloS one - 1 Jan 2011
Hoang Tong V, Toan Nguyen L, Song Le H, Ouf Eman Abou, Bock C-Thomas, Kremsner Peter G, Kun Jürgen F J, Velavan T P
Abstract excerpt
Human Ficolin-2 (L-ficolins) encoded by FCN2 gene is a soluble serum protein that plays an important role in innate immunity and is mainly expressed in the liver. Ficolin-2 serum levels and FCN2 single nucleotide polymorphisms were associated to several infectious diseases. We initially screened the complete FCN2 gene in 48 healthy individuals of Vietnamese ethnicity. We genotyped a Vietnamese cohort comprising...
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