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Article

RAD51D- and FANCG-dependent base substitution mutagenesis at the ATP1A1 locus in mammalian cells.

Mutation research - 1 Jun 2009

Hinz John M, Urbin Salustra S, Thompson Larry H

Abstract excerpt

Elaborate processes act at the DNA replication fork to minimize the generation of chromatid discontinuity when lesions are encountered. To prevent collapse of stalled replication forks, mutagenic translesion synthesis (TLS) polymerases are recruited temporarily to bypass DNA lesions. When a replication-associated (one-ended) double-strand break occurs, homologous recombination repair (HRR) can restore chromatid...

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Source

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Identifiers

PMID: 19427512
DOI: 10.1016/j.mrfmmm.2009.03.001
PMCID: PMC2692916

Genes

FANCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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