Article
Impairment of homologous recombination control in a Fanconi anemia-like Chinese hamster cell mutant.
Biology of the cell - 1 Sept 2004
Larminat Florence, Germanier Maryse, Papouli Efterpi, Defais Martine
Abstract excerpt
DNA interstrand cross-links (ICL)-inducing agents such as cisplatin, mitomycin C (MMC) and nitrogen mustards are widely used as potent antitumor drugs. Although ICL repair mechanism is not yet well characterized in mammalian cells, this pathway is thought to involve a sequential action of nucleotide excision repair (NER) and homologous recombination (HR). The importance of unraveling ICL repair pathways is...
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