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Article

Human Mus81 and FANCB independently contribute to repair of DNA damage during replication.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Oct 2007

Nomura Yuji, Adachi Noritaka, Koyama Hideki

Abstract excerpt

Recent studies suggest a crucial role for homologous recombination (HR) in repairing replication-associated DNA lesions. In mammals, the Mus81 endonuclease and the Fanconi anemia (FA) pathway have been implicated in HR repair; however, their functional relationship has remained unexplored. Here, we knockout the genes for Mus81 and FANCB, a component of the FA core complex, in the human Nalm-6 cell line. We show...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17903171
DOI: 10.1111/j.1365-2443.2007.01124.x

Genes

FANCB
FANCD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Human Mus81 and FANCB independently contribute to repair of DNA damage during replication.PMID 17903171Read ↗

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