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Article

Molecular markers of ionizing radiation-induced gene mutations in mammalian cells.

Environmental health perspectives - 1 May 1996

Hsie A W, Porter R C, Xu Z, Yu Y, Sun J, Meltz M L, Schwartz J L

Abstract excerpt

We have isolated independent Chinese hamster ovary (CHO) cell mutants at the hypoxanthine guanine phosphoribosyltransferase (hprt) locus from untreated, 60Co gamma-ray-exposed, and 212Bi alpha-exposed cells and identified the molecular changes underlying the mutation determined by multiplex polym...

Topics

Alpha Particles
Animals
CHO Cells
Cell Line
Cricetinae
DNA
Gamma Rays
Hypoxanthine Phosphoribosyltransferase
Linear Energy Transfer
Mutation
Radiation, Ionizing
Sequence Deletion

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Identifiers

PMID: 8781403
DOI: 10.1289/ehp.96104s3675
PMCID: PMC1469617

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8781403-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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