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Article

A new animal model of postsurgical bowel inflammation and fibrosis: the effect of commensal microflora.

Gut - 1 Aug 2009

Rigby R J, Hunt M R, Scull B P, Simmons J G, Speck K E, Helmrath M A, Lund P K

Abstract excerpt

OBJECTIVE: Ileocaecal resection (ICR) is common in Crohn's disease. Inflammation and fibrosis frequently recur at the site of anastomosis or in the small intestine (SI). No animal models of postsurgical inflammation and fibrosis exist. A model of ICR was developed in interleukin 10 (IL10) null and wild-type (WT) mice to test the hypothesis that ICR promotes postsurgical inflammation and fibrosis in the SI or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19398439
DOI: 10.1136/gut.2008.157636
PMCID: PMC2752281

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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