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Article

Giardia Infection of the Small Intestine Induces Chronic Colitis in Genetically Susceptible Hosts.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 2018

Dann Sara M, Le Christine H Y, Hanson Elaine M, Ross Matthew C, Eckmann Lars

Abstract excerpt

The lumen-dwelling protozoan Giardia is an important parasitic cause of diarrheal disease worldwide. Infection can persist over extended periods with minimal intestinal inflammation, suggesting that Giardia may attenuate host responses to ensure its survival, although clearance eventually occurs in most cases. IL-10 is an anti-inflammatory regulator critical for intestinal homeostasis and controlling host...

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Identifiers

PMID: 29898958
DOI: 10.4049/jimmunol.1700824
PMCID: PMC7351291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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