Article
Variable phenotypes of enterocolitis in interleukin 10-deficient mice monoassociated with two different commensal bacteria.
Gastroenterology - 1 Apr 2005
Kim Sandra C, Tonkonogy Susan L, Albright Carol A, Tsang Julia, Balish Edward J, Braun Jonathon, Huycke Mark M, Sartor R Balfour
Abstract excerpt
BACKGROUND & AIMS: To explore the hypothesis that selective immune responses to distinct components of the intestinal microflora induce intestinal inflammation, we characterized disease kinetics and bacterial antigen-specific T-cell responses in ex germ-free interleukin 10 -/- and wild-type control mice monoassociated with Enterococcus faecalis , Escherichia coli , or Pseudomonas fluorescens . METHODS: Colitis...
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