Article

Yersiniabactin producing AIEC promote inflammation-associated fibrosis in gnotobiotic <i> Il10 <sup>−/−</sup> </i> mice

2019-08-02

Abstract excerpt

Fibrosis is a significant complication of intestinal disorders associated with microbial dysbiosis and pathobiont expansion, notably Crohn’s disease (CD). Mechanisms that favor fibrosis are not well understood and therapeutic strategies are limited. Here we demonstrate that colitis susceptible Il10 -deficient mice develop inflammation-associated fibrosis when mono-associated with adherent/invasive Escherichia co...

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Literature Corpus work: 3c9efdab-3609-55cd-a9d8-968223818175
DOI: 10.1101/723148

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