Lessons from genetic models of inflammatory bowel disease.

Abstract excerpt

Over the past few years, application of targeted gene deletion and transgenic approaches has led to the often unanticipated development of rodent lines which develop inflammatory bowel disease. While none of these lines recapitulate the histopathological and clinical features usually associated w...

Topics

• Animals
• Disease Models, Animal
• Gene Deletion
• Humans
• Immunity, Mucosal
• Inflammatory Bowel Diseases
• Intestinal Mucosa
• Mice
• Mice, Transgenic
• Models, Genetic
• Mutation