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Article

Neonatal co-infection with helicobacter species markedly accelerates the development of inflammation-associated colonic neoplasia in IL-10(-/-) mice.

Helicobacter - 1 Dec 2007

Hale Laura P, Perera Dinushi, Gottfried Marcia R, Maggio-Price Lillian, Srinivasan Sudha, Marchuk Douglas

Abstract excerpt

BACKGROUND: Inflammatory bowel disease (IBD) is hypothesized to represent an aberrant immune response against enteric bacteria that occurs in a genetically susceptible host. Humans and mice with IBD are at markedly increased risk for colonic neoplasia. However, the long lead time required before development of inflammation-associated colon neoplasia in commonly used murine models of IBD slows the development of...

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PMID: 18001399
DOI: 10.1111/j.1523-5378.2007.00552.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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