Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chronic enteric salmonella infection in mice leads to severe and persistent intestinal fibrosis.

Gastroenterology - 1 Mar 2008

Grassl Guntram A, Valdez Yanet, Bergstrom Kirk S B, Vallance Bruce A, Finlay B Brett

Abstract excerpt

BACKGROUND & AIMS: Intestinal fibrosis and stricture formation are serious complications of Crohn's disease, often requiring surgical intervention. Unfortunately, the mechanisms underlying intestinal fibrosis development are poorly understood, in part because of the lack of relevant animal models. Here, we present a novel murine model of severe and persistent intestinal fibrosis caused by chronic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cecum
Share to Collagen Type I
Share to Colon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Connective Tissue Growth Factor

Share to Immediate-Early Proteins

Share to Intestinal Diseases

Share to Salmonella Infections

Share to Streptomycin

Source

Identifiers

PMID: 18325390
DOI: 10.1053/j.gastro.2007.12.043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chronic enteric salmonella infection in mice leads to severe and persistent intestinal fibrosis.PMID 18325390Read ↗

A new animal model of postsurgical bowel inflammation and fibrosis: the effect of commensal microflora.Semantic proximity Read ↗

Persistent Salmonella enterica serovar Typhimurium Infection Increases the Susceptibility of Mice to Develop Intestinal Inflammation.Semantic proximity Read ↗

IL-22 Preserves Gut Epithelial Integrity and Promotes Disease Remission during Chronic Salmonella InfectionSemantic proximity Read ↗

Giardia Infection of the Small Intestine Induces Chronic Colitis in Genetically Susceptible Hosts.Semantic proximity Read ↗

The streptomycin mouse model for <i>Salmonella</i> diarrhea: functional analysis of the microbiota, the pathogen’s virulence factors, and the host’s mucosal immune responseSemantic proximity Read ↗

Yersiniabactin producing AIEC promote inflammation-associated fibrosis in gnotobiotic <i> Il10 <sup>−/−</sup> </i> miceSemantic proximity Read ↗

Anti-fibrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn's Disease.Semantic proximity Read ↗

Loss of IL-10 signaling promotes IL-22 dependent host defenses against acute <i>Clostridioides difficile</i> infectionSemantic proximity Read ↗

TGF-beta1 gene transfer to the mouse colon leads to intestinal fibrosis.Semantic proximity Read ↗

Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice.Semantic proximity Read ↗

Interleukin-10-deficient mice develop chronic enterocolitis.Semantic proximity Read ↗

M2 Macrophages and Phenotypic Modulation of Intestinal Smooth Muscle Cells Characterize Inflammatory Stricture Formation in Rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.