Article
HLA-DRB1: genetic susceptibility and disability progression in a Spanish multiple sclerosis population.
European journal of neurology - 1 Feb 2011
Romero-Pinel L, Pujal J M, Martínez-Yélamos S, Gubieras L, Matas E, Bau L, Torrabadella M, Azqueta C, Arbizu T
Abstract excerpt
BACKGROUND AND OBJECTIVE: The association of HLA-DRB1*15 with susceptibility to multiple sclerosis (MS) has been consistently reported although its effect on the clinical phenotype is still controversial. The objectives of this study are to investigate the influence of the HLA-DRB1 alleles on the genetic susceptibility to MS and to study their impact on disability progression in a Spanish population. METHODS:...
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