Article
The role of HLA-DRB1 alleles on susceptibility and outcome of a Portuguese Multiple Sclerosis population.
Journal of the neurological sciences - 15 Jul 2007
Silva Ana Martins, Pereira Clara, Bettencourt Andreia, Carvalho Cláudia, Couto Ana Rita, Leite Maria Isabel, Marta Mónica, Freijo Marta, Costa Paulo Pinho, Mendonça Denisa, Monteiro Luís, Armas Jácome Bruges, Martins Berta
Abstract excerpt
BACKGROUND: The association between susceptibility to multiple sclerosis (MS) and HLA-DRB1*15 has been reported in various European populations. OBJECTIVE: To investigate the relationship between MS, HLA-DRB1*15 and other DRB1 alleles in a Portuguese population and their association with clinical course of MS. METHODS: The HLA-DRB1 alleles were analyzed by PCR-SSP in 248 MS patients and 282 healthy controls. In...
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