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Article

Human TRIM5alpha expression levels and reduced susceptibility to HIV-1 infection.

The Journal of infectious diseases - 1 Jun 2009

Sewram Shamman, Singh Ravesh, Kormuth Emil, Werner Lise, Mlisana Koleka, Karim S S Abdool, Ndung'u Thumbi

Abstract excerpt

BACKGROUND: Human TRIM5alpha (TRIM5alphahu), a member of the tripartite motif protein family, displays some anti-human immunodeficiency virus type 1 (HIV-1) activity in vitro, although it is substantially less potent than its rhesus monkey counterpart (TRIM5alpharh). The effects of levels of TRIM5alphahu on prevention or control of HIV-1 infection in vivo are unknown. METHODS: We used a quantitative real-time...

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Source

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Identifiers

PMID: 19388851
DOI: 10.1086/598861
PMCID: PMC2725358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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