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Article

TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys.

PLoS pathogens - 22 Jan 2010

Lim So-Yon, Rogers Thomas, Chan Tiffany, Whitney James B, Kim Jonghwa, Sodroski Joseph, Letvin Norman L

Abstract excerpt

The cytoplasmic TRIM5alpha proteins of certain mammalian lineages efficiently recognize the incoming capsids of particular retroviruses and potently restrict infection in a species-specific manner. Successful retroviruses have evolved capsids that are less efficiently recognized by the TRIM5alpha proteins of the natural hosts. To address whether TRIM5alpha contributes to the outcome of retroviral infection in a...

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Source

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Identifiers

PMID: 20107597
DOI: 10.1371/journal.ppat.1000738
PMCID: PMC2809762

Genes

TRIM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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