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Article

Rhesus macaque TRIM5 alleles have divergent antiretroviral specificities.

Journal of virology - 1 Jul 2008

Wilson Sam J, Webb Benjamin L J, Maplanka Charlotte, Newman Ruchi M, Verschoor Ernst J, Heeney Jonathan L, Towers Greg J

Abstract excerpt

TRIM5alpha is a potent barrier to cross-species retroviral transmission, and TRIM5alphas from different species have divergent antiretroviral specificities. Multiple TRIM5 alleles circulate within rhesus macaque populations. Here we show that they too have different antiretroviral specificities, highlighting how TRIM5 genotypes contribute to protection in an individual or a population.

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Source

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Identifiers

PMID: 18480454
DOI: 10.1128/JVI.00307-08
PMCID: PMC2446970

Genes

TRIM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Rhesus macaque TRIM5 alleles have divergent antiretroviral specificities.PMID 18480454Read ↗

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