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Article

The role of tripartite motif family members in mediating susceptibility to HIV-1 infection

17 Jan 2012

Abstract excerpt

PURPOSE OF REVIEW: This review highlights new roles of the large family of tripartite motif (TRIM) proteins in antiviral defense. RECENT FINDINGS: Recent research explores the participation of several TRIM family members in regulating the innate immune response. A large number of TRIM genes are upregulated upon treatment by interferon and are directly involved in signaling (TRIM5, 13, 16, 20, 21, 22, 23, 25, 27,...

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Identifiers

PMID: 22258502
DOI: 10.1097/coh.0b013e32835048e1

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