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Article

Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein.

BMC cell biology - 19 Feb 2009

Pollitt Alice Y, Insall Robert H

Abstract excerpt

BACKGROUND: SCAR/WAVE proteins couple signalling to actin polymerization, and are thus fundamental to the formation of pseudopods and lamellipods. They are controlled as part of a five-membered complex that includes the tiny HSPC300 protein. It is not known why SCAR/WAVE is found in such a large assembly, but in Dictyostelium the four larger subunits have different, clearly delineated functions. RESULTS: We have...

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Identifiers

PMID: 19228419
DOI: 10.1186/1471-2121-10-13
PMCID: PMC2652429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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