Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development.

The Journal of cell biology - 7 Sept 1998

Bear J E, Rawls J F, Saxe C L

Abstract excerpt

G protein-coupled receptors trigger the reorganization of the actin cytoskeleton in many cell types, but the steps in this signal transduction cascade are poorly understood. During Dictyostelium development, extracellular cAMP functions as a chemoattractant and morphogenetic signal that is transduced via a family of G protein-coupled receptors, the cARs. In a strain where the cAR2 receptor gene is disrupted by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cloning, Molecular
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Molecular Sequence Data

Share to Phenotype

Share to RNA, Messenger

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 9732292
DOI: 10.1083/jcb.142.5.1325
PMCID: PMC2149354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development.PMID 9732292Read ↗

Nap1 regulates Dictyostelium cell motility and adhesion through SCAR-dependent and -independent pathways.Semantic proximity Read ↗

SCAR is a primary regulator of Arp2/3-dependent morphological events in DrosophilaSemantic proximity Read ↗

Loss of RapC causes defects in cytokinesis, cell migration, and multicellular development of Dictyostelium.Semantic proximity Read ↗

The WAVE/SCAR complex promotes polarized cell movements and actin enrichment in epithelia during C. elegans embryogenesis.Semantic proximity Read ↗

Dictyostelium RasG is required for normal motility and cytokinesis, but not growth.Semantic proximity Read ↗

Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein.Semantic proximity Read ↗

Costars, a Dictyostelium protein similar to the C-terminal domain of STARS, regulates the actin cytoskeleton and motility.Semantic proximity Read ↗

A new HECT ubiquitin ligase regulating chemotaxis and development in Dictyostelium discoideum.Semantic proximity Read ↗

Abi mutants in Dictyostelium reveal specific roles for the SCAR/WAVE complex in cytokinesis.Semantic proximity Read ↗

PIP₃-dependent macropinocytosis is incompatible with chemotaxis.Semantic proximity Read ↗

WAVE/SCAR, a multifunctional complex coordinating different aspects of neuronal connectivity.Semantic proximity Read ↗

Coronin7 regulates WASP and SCAR through CRIB mediated interaction with Rac proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.