Article
SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development.
The Journal of cell biology - 7 Sept 1998
Bear J E, Rawls J F, Saxe C L
Abstract excerpt
G protein-coupled receptors trigger the reorganization of the actin cytoskeleton in many cell types, but the steps in this signal transduction cascade are poorly understood. During Dictyostelium development, extracellular cAMP functions as a chemoattractant and morphogenetic signal that is transd...
Topics
- Amino Acid Sequence
- Animals
- Cell Movement
- Cell Size
- Cloning, Molecular
- Dictyostelium
- Fungal Proteins
- GTP-Binding Proteins
- Gene Targeting
- Immunohistochemistry
- Molecular Sequence Data
- Phenotype
- Proteins
- Protozoan Proteins
- RNA, Messenger
- Receptors, Cell Surface
- Sequence Alignment
- Sequence Analysis, DNA