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Article

A ubiquitin-conjugating enzyme is essential for developmental transitions in Dictyostelium.

Molecular biology of the cell - 1 Oct 1997

Clark A, Nomura A, Mohanty S, Firtel R A

Abstract excerpt

We have identified a developmentally essential gene, UbcB, by insertional mutagenesis. The encoded protein (UBC1) shows very high amino acid sequence identity to ubiquitin-conjugating enzymes from other organisms, suggesting that UBC1 is involved in protein ubiquitination and possibly degradation during Dictyostelium development. Consistent with the homology of the UBC1 protein to UBCs, the developmental pattern...

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Identifiers

PMID: 9348538
DOI: 10.1091/mbc.8.10.1989
PMCID: PMC25659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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