Article
Abi mutants in Dictyostelium reveal specific roles for the SCAR/WAVE complex in cytokinesis.
Current biology : CB - 12 Feb 2008
Pollitt Alice Y, Insall Robert H
Abstract excerpt
Actin polymerization drives multiple cell processes involving movement and shape change. SCAR/WAVE proteins connect signaling to actin polymerization through the activation of the Arp2/3 complex. SCAR/WAVE is normally found in a complex with four other proteins: PIR121, Nap1, Abi2,and HSPC300 (Fi...
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