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Article

LagC is required for cell-cell interactions that are essential for cell-type differentiation in Dictyostelium.

Genes & development - 15 Apr 1994

Dynes J L, Clark A M, Shaulsky G, Kuspa A, Loomis W F, Firtel R A

Abstract excerpt

Strain AK127 is a developmental mutant of Dictyostelium discoideum that was isolated by restriction enzyme-mediated integration (REMI). Mutant cells aggregate normally but are unable to proceed past the loose aggregate stage. The cloned gene, lagC (loose aggregate C), encodes a novel protein of 98 kD that contains an amino-terminal signal sequence and a putative carboxy-terminal transmembrane domain. The mutant...

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Identifiers

PMID: 7926779
DOI: 10.1101/gad.8.8.948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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