Article
Cell motility and SCAR localisation in axenically growing Dictyostelium cells.
European journal of cell biology - 1 Sept 2006
Pollitt Alice Y, Blagg Simone L, Ibarra Neysi, Insall Robert H
Abstract excerpt
Dictyostelium is a popular experimental organism, in particular for studies of actin dynamics, cell motility and chemotaxis. We find that the motility of axenic cells is unexpectedly different from other strains during growth. In particular, vegetative AX3 cells do not show detectable localisation of SCAR and its regulatory complex to actin-rich protrusions such as filopodia and pseudopodia. Similarly, a range of...
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