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Article

The complex interaction between APOE promoter and AD: an Italian case-control study.

European journal of human genetics : EJHG - 1 Jul 2009

Bizzarro Alessandra, Seripa Davide, Acciarri Adele, Matera Maria Giovanna, Pilotto Alberto, Tiziano Francesco Danilo, Brahe Christina, Masullo Carlo

Abstract excerpt

The single nucleotide polymorphisms (SNPs) rs449647, rs769446 and rs405509 in the promoter region of the APOE gene have been variously suggested to be epsilon 4-independent risk factors for Alzheimer's disease (AD). A previous Italian study found that the rs449647 was significantly associated with late-onset AD. The aim of this study was to verify whether these APOE promoter SNPs are genetic risk factors for AD...

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Share to Alzheimer Disease
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Source

Open in PubMed Open full text

Identifiers

PMID: 19172988
DOI: 10.1038/ejhg.2008.263
PMCID: PMC2986491

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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