Article
Apolipoprotein E promoter polymorphisms and risk of Alzheimer's disease: evidence from meta-analysis.
Journal of Alzheimer's disease : JAD - 1 Jan 2010
Xin Xiao-Yu, Ding Jian-Qing, Chen Sheng-Di
Abstract excerpt
Apolipoprotein E (APOE) promoter polymorphisms have long been linked to Alzheimer disease (AD) susceptibility, although the established data remains controversial. Using meta-analysis, our study aimed to clarify the nature of the genetic risks contributed by the three polymorphisms for developing AD. Medline, Embase, and Alzgene search identified 40 studies with 9,662 cases and 9.696 controls. Both -491A/T...
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