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Article

Apolipoprotein E promoter polymorphisms and risk of Alzheimer's disease: evidence from meta-analysis.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Xin Xiao-Yu, Ding Jian-Qing, Chen Sheng-Di

Abstract excerpt

Apolipoprotein E (APOE) promoter polymorphisms have long been linked to Alzheimer disease (AD) susceptibility, although the established data remains controversial. Using meta-analysis, our study aimed to clarify the nature of the genetic risks contributed by the three polymorphisms for developing AD. Medline, Embase, and Alzgene search identified 40 studies with 9,662 cases and 9.696 controls. Both -491A/T...

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Alzheimer Disease
Apolipoprotein E4
Genetic Markers
Haplotypes
Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Promoter Regions, Genetic

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Identifiers

PMID: 20061606
DOI: 10.3233/JAD-2010-1329

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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