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Genetic variations of the SLCO1B1 gene in the Chinese, Malay and Indian populations of Singapore.

Drug metabolism and pharmacokinetics - 1 Jan 2008

Ho Woon Fei, Koo Seok Hwee, Yee Jie Yin, Lee Edmund Jon Deoon

Abstract excerpt

OATP1B1 is a liver-specific transporter that mediates the uptake of various endogenous and exogenous compounds including many clinically used drugs from blood into hepatocytes. This study aims to identify genetic variations of SLCO1B1 gene in three distinct ethnic groups of the Singaporean population (n=288). The coding region of the gene encoding the transporter protein was screened for genetic variations in the...

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PMID: 19122343
DOI: 10.2133/dmpk.23.476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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