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Article

Global analysis of genetic variation in SLCO1B1.

Pharmacogenomics - 1 Jan 2008

Pasanen Marja K, Neuvonen Pertti J, Niemi Mikko

Abstract excerpt

INTRODUCTION: Organic anion transporting polypeptide 1B1 (OATP1B1), encoded by the SLCO1B1 gene, mediates the hepatic uptake of endogenous compounds and xenobiotics, including drugs. The aim of this study was to investigate the diversity of the SLCO1B1 gene at the global level. MATERIALS AND METHODS: Distribution of SLCO1B1 alleles was determined in 941 individuals from 52 populations comprising Africa, the...

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Alleles
DNA
Ethnicity
Gene Frequency
Haplotypes
Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver-Specific Organic Anion Transporter 1

Organic Anion Transporters

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PMID: 18154446
DOI: 10.2217/14622416.9.1.19

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