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Article

Frequency of functional exonic single-nucleotide polymorphisms and haplotype distribution in the SLCO1B1 gene across genetic ancestry groups in the Qatari population.

Scientific reports - 1 Sept 2022

Dashti Mohammed, Al-Matrouk Abdullah, Channanath Arshad, Al-Mulla Fahd, Thanaraj Thangavel Alphonse

Abstract excerpt

Organic anion transporting polypeptides (OATP), which are encoded by SLCO genes, participate in the hepatic elimination of drugs and xenobiotics. SLCO1B1 is an important pharmacogenomic gene (encoding OATP1B1) associated with response to the uptake of endogenous compounds, such as statin and bilirubin. Ethnicity of the patient modulates the response to these drugs; the frequency and haplotype data for SLCO1B1...

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Exons
Gene Frequency
Genotype
Haplotypes
Liver-Specific Organic Anion Transporter 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Organic Anion Transporters

Polymorphism, Single Nucleotide

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Identifiers

PMID: 36050458
DOI: 10.1038/s41598-022-19318-x
PMCID: PMC9437070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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