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Article

Comparison of SLCO1B1 sequence variability among German, Turkish, and African populations.

European journal of clinical pharmacology - 1 Mar 2008

Mwinyi Jessica, Köpke Karla, Schaefer Melanie, Roots Ivar, Gerloff Thomas

Abstract excerpt

BACKGROUND: OATP1B1 is one of the key hepatocellular uptake transporters providing extraction of diverse compounds, including bile acids, xenobiotics, and a variety of drugs, from portal venous blood into the liver. Polymorphisms of the SLCO1B1 gene have been demonstrated to influence in vitro transport function and the pharmacokinetic profile of compounds. OBJECTIVE: The goal of our study was the comparison of...

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PMID: 18185926
DOI: 10.1007/s00228-007-0409-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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