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Genetic variations of the SLC22A4 gene in Chinese and Indian populations of Singapore.

Drug metabolism and pharmacokinetics - 1 Jan 2009

Toh Dorothy Su Lin, Koo Seok Hwee, Limenta Lie Michael George, Yee Jie Yin, Murray Michael, Lee Edmund Jon Deoon

Abstract excerpt

The novel organic cation transporter 1 (OCTN1) is a multispecific, bidirectional and pH-dependent organic cation transporter with low carnitine transport activity. It is a transporter of the physiological substance ergothioneine and mediates the transport of a variety of organic cations such as tetraethylammonium, pyrilamine and quinidine. This study identifies genetic variations of the SLC22A4 gene in two...

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PMID: 19881261
DOI: 10.2133/dmpk.24.475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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