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Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3: genetic variability and haplotype analysis in white Canadians.

Drug metabolism and pharmacokinetics - 1 Jan 2010

Boivin Andrée-Anne, Cardinal Héloïse, Barama Azemi, Pichette Vincent, Hébert Marie-Josée, Roger Michel

Abstract excerpt

Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3 are human hepatocyte transporters that mediate the uptake of various endogenous and exogenous substances. Genetic variations in solute carrier transporter 1B1 (SLCO1B1) and SLCO1B3 genes, which encode OATP1B1 and OATP1B3 proteins, could affect the pharmacokinetics of drugs leading to interindividual differences in drug responses. The full extent of...

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PMID: 20877131
DOI: 10.2133/dmpk.dmpk-10-sh-046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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