Article
Comparison of genetic variations of the SLCO1B1, SLCO1B3, and SLCO2B1 genes among five ethnic groups.
Environmental toxicology and pharmacology - 1 Nov 2015
Namgoong Suhg, Cheong Hyun Sub, Kim Ji On, Kim Lyoung Hyo, Na Han Sung, Koh In Song, Chung Myeon Woo, Shin Hyoung Doo
Abstract excerpt
Organic anion-transporting polypeptide (OATP; gene symbol, SLCO) transporters are generally involved in the uptake of multiple drugs and their metabolites at most epithelial barriers. The pattern of single-nucleotide polymorphisms (SNPs) in these transporters may be determinants of interindividual variability in drug disposition and response. The objective of this study was to define the distribution of SNPs of...
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