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Article

Common germline variation in mismatch repair genes and survival after a diagnosis of colorectal cancer.

International journal of cancer - 15 Apr 2009

Koessler Thibaud, Azzato Elizabeth M, Perkins Barbara, Macinnis Robert J, Greenberg David, Easton Douglas F, Pharoah Paul D P

Abstract excerpt

The mismatch repair (MMR) genes are involved in the maintenance of genomic integrity. Recently, we showed that common variants in these genes are unlikely to contribute significantly to colorectal cancer risk. The aim of this study was to investigate the role of common variants in the mismatch repair pathway as prognostic markers in colorectal cancer patients. We genotyped 2,060 patients for 68 SNPs in 7 mismatch...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19115210
DOI: 10.1002/ijc.24120

Genes

MSH3
MLH1
MLH3
MSH2
MSH6
PMS1
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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