Article
DNA Mismatch Repair Gene Variants in Sporadic Solid Cancers.
International journal of molecular sciences - 3 Aug 2020
Caja Fabian, Vodickova Ludmila, Kral Jan, Vymetalkova Veronika, Naccarati Alessio, Vodicka Pavel
Abstract excerpt
The phenotypic effects of single nucleotide polymorphisms (SNPs) in the development of sporadic solid cancers are still scarce. The aim of this review was to summarise and analyse published data on the associations between SNPs in mismatch repair genes and various cancers. The mismatch repair system plays a unique role in the control of the genetic integrity and it is often inactivated (germline and somatic...
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