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Common variants in mismatch repair genes and risk of invasive ovarian cancer.

Carcinogenesis - 1 Nov 2006

Song Honglin, Ramus Susan J, Quaye Lydia, DiCioccio Richard A, Tyrer Jonathan, Lomas Emma, Shadforth Danielle, Hogdall Estrid, Hogdall Claus, McGuire Valerie, Whittemore Alice S, Easton Douglas F, Ponder Bruce A J, Kjaer Susanne Kruger, Pharoah Paul D P, Gayther Simon A

Abstract excerpt

Mismatch repair (MMR) is important for repairing of nucleotide mismatches during DNA replication. Germline mutations in MMR genes are associated with hereditary non-polyposis colorectal cancer (HNPCC). Ovarian cancer occurs as part of the HNPCC phenotype, and so common variants in MMR genes are candidates for ovarian cancer susceptibility. We performed a large multicentre case-control study to investigate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16774946
DOI: 10.1093/carcin/bgl089

Genes

PMS2
MSH3
MSH6
MLH1
MLH3
MSH2
PMS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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