Article
Mismatch repair polymorphisms and the risk of colorectal cancer.
International journal of cancer - 1 Apr 2007
Berndt Sonja I, Platz Elizabeth A, Fallin M Daniele, Thuita Lucy W, Hoffman Sandra C, Helzlsouer Kathy J
Abstract excerpt
Rare germline variants in mismatch repair genes have been linked to hereditary nonpolyposis colorectal cancer; however, it is unknown whether common polymorphisms in these genes alter the risk of colorectal cancer. To examine the association between common variants in mismatch repair genes and colorectal cancer, we conducted a case-cohort study within the CLUE II cohort. Four single nucleotide polymorphisms in 3...
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