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Article

Common variants in mismatch repair genes and risk of colorectal cancer.

Gut - 1 Aug 2008

Koessler T, Oestergaard M Z, Song H, Tyrer J, Perkins B, Dunning A M, Easton D F, Pharoah P D P

Abstract excerpt

BACKGROUND AND AIMS: The mismatch repair (MMR) genes are in charge of maintaining genomic integrity. Mutations in the MMR genes are at the origin of a familial form of colorectal cancer (CRC). This syndrome accounts for only a small proportion of the excess familial risk of CRC. The characteristi...

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Source

Identifiers

PMID: 18364438
DOI: 10.1136/gut.2007.137265

Genes

MLH1
MSH2
MSH3
MSH6
MLH3
PMS1
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18364438-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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