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Article

The prognostic significance of polymorphisms in hMLH1/hMSH2 for colorectal cancer.

Medical oncology (Northwood, London, England) - 1 Jun 2014

Wang Yibaina, Li Guangxiao, Hu Fulan, Bi Haoran, Wu Zhiwei, Zhao Xiaojuan, Li Ye, Li Shuying, Li Dandan, Cui Binbin, Dong Xinshu, Zhao Yashuang

Abstract excerpt

We aimed to investigate the associations between single-nucleotide polymorphisms (SNPs) in two mismatch repair genes (hMLH1 and hMSH2) and colorectal cancer (CRC) prognosis in Northeast China. We genotyped 387 patients for 10 SNPs in hMLH1 and hMSH2, using polymerase chain reaction restriction fragment length polymorphism approach. Associations between genotypes and overall survival (OS) were estimated using...

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PMID: 24793746
DOI: 10.1007/s12032-014-0975-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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