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Highly parallel identification of essential genes in cancer cells

17 Dec 2008

Abstract excerpt

More complete knowledge of the molecular mechanisms underlying cancer will improve prevention, diagnosis and treatment. Efforts such as The Cancer Genome Atlas are systematically characterizing the structural basis of cancer, by identifying the genomic mutations associated with each cancer type. A powerful complementary approach is to systematically characterize the functional basis of cancer, by identifying the...

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PMID: 19091943
DOI: 10.1073/pnas.0810485105

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