Article
Saccharomyces cerevisiae Med9 comprises two functionally distinct domains that play different roles in transcriptional regulation.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jan 2009
Takahashi Hiroyuki, Kasahara Koji, Kokubo Tetsuro
Abstract excerpt
Mediator is one of the most important co-activators that function in eukaryotic transcriptional regulation. In Saccharomyces cerevisiae, Mediator is comprised of 25 subunits belonging to four structurally distinct modules: Head, Middle, Tail, and Cyc-C. Although each module plays a critical role in the regulation of a distinct set of genes, the precise molecular mechanisms remain unclear. To gain new insight into...
Topics
- Electrophoresis, Gel, Two-Dimensional
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Mediator Complex
- Mutation
- Protein Binding
- Protein Structure, Tertiary
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Structure-Activity Relationship