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Article

Functional and physical interactions within the middle domain of the yeast mediator.

Molecular genetics and genomics : MGG - 1 Aug 2006

Hallberg Magnus, Hu Guo-Zhen, Tronnersjö Susanna, Adler David, Balciunas Darius, Björklund Stefan, Ronne Hans

Abstract excerpt

Med21 (Srb7) is a small essential subunit of the middle domain of the Mediator, which is conserved in all eukaryotes. It is thought to play an important role in both transcriptional activation and repression. In the yeast Saccharomyces cerevisiae, Med21 is known to interact both with the Mediator subunit Med6 and the global co-repressor Tup1. We have made a temperature-sensitive med21-ts mutant, which we used in...

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Source

Identifiers

PMID: 16758199
DOI: 10.1007/s00438-006-0135-7

Genes

MED10
MED7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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