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Article

Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation.

Molecular and cellular biology - 1 Feb 1999

Han S J, Lee Y C, Gim B S, Ryu G H, Park S J, Lane W S, Kim Y J

Abstract excerpt

The multisubunit Mediator complex of Saccharomyces cerevisiae is required for most RNA polymerase II (Pol II) transcription. The Mediator complex is composed of two subcomplexes, the Rgr1 and Srb4 subcomplexes, which appear to function in the reception of activator signals and the subsequent modulation of Pol II activity, respectively. In order to determine the precise composition of the Mediator complex and to...

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Identifiers

PMID: 9891034
DOI: 10.1128/MCB.19.2.979
PMCID: PMC116029

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Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation.PMID 9891034Read ↗

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Direct interaction of RNA polymerase II and mediator required for transcription in vivo.Semantic proximity Read ↗

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Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions.Semantic proximity Read ↗

An activator binding module of yeast RNA polymerase II holoenzyme.Semantic proximity Read ↗

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A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans.Semantic proximity Read ↗

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