Article
Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation.
Molecular and cellular biology - 1 Feb 1999
Han S J, Lee Y C, Gim B S, Ryu G H, Park S J, Lane W S, Kim Y J
Abstract excerpt
The multisubunit Mediator complex of Saccharomyces cerevisiae is required for most RNA polymerase II (Pol II) transcription. The Mediator complex is composed of two subcomplexes, the Rgr1 and Srb4 subcomplexes, which appear to function in the reception of activator signals and the subsequent modu...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA Polymerase II
- DNA Primers
- Fungal Proteins
- Genes, Fungal
- Holoenzymes
- Humans
- Macromolecular Substances
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Saccharomyces cerevisiae
- Sequence Homology, Amino Acid
- Transcriptional Activation