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Article

Association of human NAD(P)H:quinone oxidoreductase 1 (NQO1) polymorphism with development of acute lung injury.

Journal of cellular and molecular medicine - 1 Aug 2009

Reddy Anita J, Christie Jason D, Aplenc Richard, Fuchs Barry, Lanken Paul N, Kleeberger Steven R

Abstract excerpt

Acute lung injury (ALI) is a syndrome with significant morbidity and mortality, but its genetic susceptibility is not clearly understood. In the present study, we characterized functional promoter single nucleotide polymorphisms (SNPs) in the phase II antioxidant gene NQO1 (NAD(P)H:quinone oxidor...

Topics

Acute Lung Injury
Adult
Cell Line
Cohort Studies
Female
Genetic Predisposition to Disease
Humans
Male
Middle Aged
NAD(P)H Dehydrogenase (Quinone)
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 19017358
DOI: 10.1111/j.1582-4934.2008.00581.x
PMCID: PMC2829347

Genes

NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-19017358-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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