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Article

Association of human NAD(P)H:quinone oxidoreductase 1 (NQO1) polymorphism with development of acute lung injury.

Journal of cellular and molecular medicine - 1 Aug 2009

Reddy Anita J, Christie Jason D, Aplenc Richard, Fuchs Barry, Lanken Paul N, Kleeberger Steven R

Abstract excerpt

Acute lung injury (ALI) is a syndrome with significant morbidity and mortality, but its genetic susceptibility is not clearly understood. In the present study, we characterized functional promoter single nucleotide polymorphisms (SNPs) in the phase II antioxidant gene NQO1 (NAD(P)H:quinone oxidoreductase1) to evaluate its role in susceptibility to ALI. Three previously uncharacterized SNPs in the NQO1 promoter...

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Source

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Identifiers

PMID: 19017358
DOI: 10.1111/j.1582-4934.2008.00581.x
PMCID: PMC2829347

Genes

NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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