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Article

Association between HO‑1 gene promoter polymorphisms and diseases (Review).

Molecular medicine reports - 1 Jan 2022

Ma Lin-Lin, Sun Lei, Wang Yu-Xi, Sun Bai-He, Li Yan-Fei, Jin Yue-Ling

Abstract excerpt

Heme oxygenase‑1 (HO‑1) is an inducible cytoprotective enzyme that degrades heme into free iron, carbon monoxide and biliverdin, which is then rapidly converted into bilirubin. These degradation products serve an important role in the regulation of inflammation, oxidative stress and apoptosis. While the expression level of HO‑1 is typically low in most cells, it may be highly expressed when induced by a variety...

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Source

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Identifiers

PMID: 34841438
DOI: 10.3892/mmr.2021.12545
PMCID: PMC8669660

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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