Article
Common variants of NFE2L2 gene predisposes to acute respiratory distress syndrome in patients with severe sepsis.
Critical care (London, England) - 16 Jun 2015
Acosta-Herrera Marialbert, Pino-Yanes Maria, Blanco Jesús, Ballesteros Juan Carlos, Ambrós Alfonso, Corrales Almudena, Gandía Francisco, Subirá Carlés, Domínguez David, Baluja Aurora, Añón José Manuel, Adalia Ramón, Pérez-Méndez Lina, Flores Carlos, Villar Jesus
Abstract excerpt
INTRODUCTION: The purpose of this study was to investigate whether common variants across the nuclear factor erythroid 2-like 2 (NFE2L2) gene contribute to the development of the acute respiratory distress syndrome (ARDS) in patients with severe sepsis. NFE2L2 is involved in the response to oxidative stress, and it has been shown to be associated with the development of ARDS in trauma patients. METHODS: We...
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