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Article

An NFKB1 promoter insertion/deletion polymorphism influences risk and outcome in acute respiratory distress syndrome among Caucasians.

PloS one - 9 May 2011

Bajwa Ednan K, Cremer Paul C, Gong Michelle N, Zhai Rihong, Su Li, Thompson B Taylor, Christiani David C

Abstract excerpt

BACKGROUND: Nuclear factor-κB (NF-κB) is required for transcription of many pro-inflammatory genes and has been implicated in the pathogenesis of acute respiratory distress syndrome (ARDS). We hypothesized that a known functional polymorphism in the promoter of the NFKB1 gene may affect susceptibility to and outcome from ARDS. METHODS: A case control study was conducted among a cohort of patients admitted to the...

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Source

Open in PubMed Open full text

Identifiers

PMID: 21573030
DOI: 10.1371/journal.pone.0019469
PMCID: PMC3090449

Genes

NFKB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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