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Article

Novel variants in the PRDX6 Gene and the risk of Acute Lung Injury following major trauma.

BMC medical genetics - 31 May 2011

Rushefski Melanie, Aplenc Richard, Meyer Nuala, Li Mingyao, Feng Rui, Lanken Paul N, Gallop Robert, Bellamy Scarlett, Localio A Russell, Feinstein Sheldon I, Fisher Aron B, Albelda Steven M, Christie Jason D

Abstract excerpt

BACKGROUND: Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is thought to be protective against oxidant injury. Little is known about genetic variation within the PRDX6 gene and its association with acute lung injury (ALI). In this study we sequenced the PRDX6 gene to uncover common variants, and tested association with ALI following major trauma. METHODS: To examine the extent of...

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Identifiers

PMID: 21627785
DOI: 10.1186/1471-2350-12-77
PMCID: PMC3121666

Genes

PRDX6

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Source receipt: pubmed, retrieved 7 Sept 2026.

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