Article
Distinct and replicable genetic risk factors for acute respiratory distress syndrome of pulmonary or extrapulmonary origin.
Journal of medical genetics - 1 Nov 2012
Tejera Paula, Meyer Nuala J, Chen Feng, Feng Rui, Zhao Yang, O'Mahony D Shane, Li Lin, Sheu Chau-Chyun, Zhai Rihong, Wang Zhaoxi, Su Li, Bajwa Ed, Ahasic Amy M, Clardy Peter F, Gong Michelle N, Frank Angela J, Lanken Paul N, Thompson B Taylor, Christie Jason D, Wurfel Mark M, O'Keefe Grant E, Christiani David C
Abstract excerpt
BACKGROUND: The role of genetics in the development of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) from direct or indirect lung injury has not been specifically investigated. The aim of this study was to identify genetic variants contributing to ALI/ARDS from pulmonary or extrapulmonary causes. METHODS: We conducted a multistage genetic association study. We first performed a large-scale...
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